Biotechnology (BIOT)
An introductory course to the field of biotechnology and application of biotechnology methodologies in emerging areas. Topics of discussion will include microbial biotechnology, animal biotechnology, forensic biotechnology, agriculture biotechnology, bioremediation and medical biotechnology. Emphasis will be placed on ethical and social considerations and opportunities for improvements in the field.
An introductory laboratory course to the field of biotechnology and application of biotechnology methodologies in emerging areas. Laboratories include aseptic technique, pipetting and measurement, NNA extration and restriction digestion, gel electrophoresis nad PCR. Lab fee required.
Methodology and application in biotechnology. The following topics will be covered: genetic engineering techniques for introducing a gene for a desired protein into a cell with vectors, techniques for growing bacteria and yeast to produce a desired protein, cell transformation by electroporation, blue/white screening for selection of a colony with successful transformation with the desired vector, identification of a plasmid with PCR and DNA sequencing, use of enzyme assays to measure protein concentration in solutions, fed-batch yeast fermentation, mammalian cell culture techniques, and analysis of protein expression by Western blot. Lab fee.
Prerequisite: BIOT-200
Introduction to bioinformatic resources/methods for biologists. Topics include: biological databases, sequence alignment, gene and protein structure prediction, molecular phylogenetics, genomics and proteomics. Students will gain practical experience with bioinformatics tools and develop basic skills in the collection and presentation of bioinformatics data.
Introduction to bioinformatic resources/methods for biologists. Topics include: biological databases, sequence alignment, gene and protein structure prediction, molecular phylogenetics, genomics and proteomics. Students will gain practical experience with bioinformatics tools and develop basic skills in the collection and presentation of bioinformatics data. This lab course must be taken concurrently with lecture BIOL-405.
Prerequisite: DSCI-100C, DSCI-100CL
Co-Requisite: BIOT-405
This course is primarily lab based and will focus on teaching the techniques necessary to maintain mammalian cells in culture and manipulating stem cells. Exercises will include hands-on training isolating, maintaining, characterizing, cryopreserving, and manipulating in vitro cells in addition to independent research experience. Additional skills will include Basic Aseptic Technique; Media Preparation; Cell counting; Survival assays, Live Cell Identification and Transfection. These skills are crucial for individuals seeking career opportunities in the biotechnology field.
Preparation for PSM Program and Bioscience Industry Engagement. Career preparation for successful entry and development in biotechnology. Community and interactive discussion topics including the business of science, career opportunities, industry and workforce trends, and overview of the biotechnology industry. Intended to help students identify career values and goals and get them on track for being successful in finding a meaningful project for their capstone experience. Students will research potential internship sites and develop a plan for securing a project. In addition to writing a resume and cover letter, students will develop interviewing and networking skills, set goals and learning objectives, and learn skills that will ensure their success in their internships or research projects.
Methodology and application in biotechnology. This course is primarily lab based and will prepare students for independent research project. The following topics will be covered: genetic engineering techniques for introducing a gene for a desired protein into a cell with vectors, techniques for growing bacteria and yeast to produce a desired protein, cell transformation by electroporation, blue/white screening for selection of a colony with successful transformation with the desired vector, identification of a plasmid with PCR and DNA sequencing, use of enzyme assays to measure protein concentration in solutions, fed-batch yeast fermentation, mammalian cell culture techniques, and analysis of protein expression by Western blot. Lab fee.
Introduction to bioinformatic resources/methods for biologists. Topics include: biological databases, sequence alignment, gene and protein structure prediction, molecular phylogenetics, genomics and proteomics. Students will gain practical experience with bioinformatics tools and develop basic skills in the collection and presentation of bioinformatics data.
Co-Requisite: BIOT-505L
Introduction to bioinformatic resources/methods for biologists. Topics include: biological databases, sequence alignment, gene and protein structure prediction, molecular phylogenetics, genomics and proteomics. Students will gain practical experience with bioinformatics tools and develop basic skills in the collection and presentation of bioinformatics data.
Co-Requisite: BIOT-505
A seminar course that examines the ethical implications of decisions made in biotechnology as well as the responsibilities of life scientists in the biomedical development process, including industry, government, and healthcare authorities and in their communities. Course discussions include stewardship and environmental impacts of biomanufacturing as well as ethical use of laboratory animals. Students examine ethical issues related to biomedical product advancement and use, and specific areas of science are also explored from a Christian ethics viewpoint through lectures, student oral presentations, team debate, and final written projects.
A course designed for science professionals to develop and apply skills and knowledge for managing business operations. Real-world business cases are used to develop students' management capacity and capability. Areas of focus include the process view of organizations, performance measures, products and product attributes, production processes, process competencies, procurement and supply chain management and regulatory requirements. The laws and regulations enforced by the Food and Drug Administration and other regulatory agencies related to the biotechnology, pharmaceutical, and medical device industries are surveyed. Included is the U.S. legal regulatory system, Food, Drug, and Cosmetic Act and related laws, Freedom of Information Act, regulation affecting foods, drugs, biologics, veterinary products, diagnostics, and devices, FDA enforcement, product liability, and import/export requirements. Reviews the impact of quality systems and the functions, roles, and responsibilities on Quality Assurance and Quality Control.
This course is primarily lab based and will focus on teaching the techniques necessary to maintain mammalian cells in culture and manipulating stem cells. Exercises will include hands-on training isolating, maintaining, characterizing, cryopreserving, and manipulating in vitro cells in addition to independent research experience. Additional skills will include Basic Aseptic Technique; Media Preparation; Cell counting; Survival assays, Live Cell Identification and Transfection. These skills are crucial for individuals seeking career opportunities in the biotechnology field.
Introduces advanced statistical concepts and analytical methods for the experimental needs and data encountered in biotechnology and biomedical sciences. Experimental design/conduct, quantitative analysis of data, and statistical inferences and interpretations are studied for scientific hypothesis testing, as well as clinical trials. Explores methodological approaches to bioassay development/testing and provides a foundation for critically evaluating information to support research findings, product claims, and technology opportunities. Students are recommended to be familiar with Python programming.
Terms Typically Offered: Fall.
This course may be taken for a maximum of four (4) units in one term. A maximum of eight (8) combined credit units apply to graduation. This course is designed with the purpose of providing students the opportunity to conduct research off-campus at STEM companies in the community. This course promotes early entry into the workplace for the student through part-time employment. This course requires actual work experience be sought in a biotech or STEM-focused business firm providing an opportunity to integrate classroom teaching in practical application under the direct supervision of the assigned instructor. Students are responsible for completing a project report and presenting their research results in BIOT-699.
A seminar course that develops skills in managing bioentrepreneurship projects in the bioscience and biomedical device fields. Students learn how to be responsive team members as well as communicative team leaders. This course also investigates issues and decisions that inventor / scientists, investors, founders, business people, lawyers, and others might typically encounter when they are considering the application and commercialization of early stage scientific discoveries. And how to sustain innovation in organizations and team dynamics.
A course that focuses on oral and written communication for both scientific and nonscientific audiences for a variety of sources in biotechnology, including journals, investor relations, and regulatory documentation. Topics include uses and management of information; decision tools and concepts; quality control.
Students conduct supervised, independent research in Biotechnology. The student and faculty supervisor together develop a course outline, with a proposal for original research and the method of evaluation, including a formal research paper. Outline must be approved by the department before the student is permitted to register. Students will present their work in oral and written format. A maximum of eight (8) combined units apply to graduation.
Seminar series with invited biology speakers including many prominent scientists and leaders working at biotechnology companies. Students will be expected to present their research at these Seminars. Graduate students are to take this course every Spring. This course is repeatable to a maximum of 3 units.